Paraxanthine instead of caffeine: what 14 rowers and 12 runners revealed about the βclean stimulantβ made from a coffee metabolite
The liver turns about 70% of caffeine into paraxanthine, and now it is sold on its own β as a stimulant without the insomnia and jitters. In a 2026 RCT in rowers, paraxanthine by itself did not speed up a 2000 m test, and in a 2024 study of a 10 km run it did not change finishing time at all. It disrupted sleep after an evening session less β but that was measured with a questionnaire.
Andrey Leskovβ’
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