#supplements

Articles tagged: supplements

9 articles

Caffeine gum: 25 studies, an effect size of 0.195 and exactly zero in people who already drink a lot of coffee

Caffeine gum: 25 studies, an effect size of 0.195 and exactly zero in people who already drink a lot of coffee

Caffeine gum is leaving its military niche and moving into running, and interest in it keeps growing. A meta-analysis published in September 2026 gathered 25 studies and 390 participants: the gain is real, it is statistically significant and it is also tiny. And in some people it is absent altogether β€” we look at who exactly, and at why you have to chew for ten minutes.

Ekaterina Gromovaβ€’
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SARMs in recreational athletes: a five-year ban for three substances, and only 52% of products that contain what the label says

SARMs in recreational athletes: a five-year ban for three substances, and only 52% of products that contain what the label says

On 11 September 2026 USADA handed a five-year ban to a 49-year-old recreational triathlete: a sample taken at an ordinary city race contained ostarine, ligandrol and exogenous testosterone. A good moment to work out what SARMs are, why nobody has ever shown an effect of theirs on endurance, and how they end up inside people who never deliberately took anything.

Maxim Belyaevβ€’
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Carnosine: 299 participants, 12 weeks at 2 grams a day and two significant results out of 126 comparisons

Carnosine: 299 participants, 12 weeks at 2 grams a day and two significant results out of 126 comparisons

Carnosine is a dipeptide that buffers acid in muscle; it and beta-alanine are sold as supplements to fight β€œacid build-up”. The largest RCT to date (JISSN, 2026) found no difference from placebo in any of seven tests across the whole group. An effect surfaced in only two subgroups. We explain why that is weaker than it sounds, and what beta-alanine does that carnosine does not.

Ekaterina Gromovaβ€’
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Paraxanthine instead of caffeine: what 14 rowers and 12 runners revealed about the β€œclean stimulant” made from a coffee metabolite

Paraxanthine instead of caffeine: what 14 rowers and 12 runners revealed about the β€œclean stimulant” made from a coffee metabolite

The liver turns about 70% of caffeine into paraxanthine, and now it is sold on its own β€” as a stimulant without the insomnia and jitters. In a 2026 RCT in rowers, paraxanthine by itself did not speed up a 2000 m test, and in a 2024 study of a 10 km run it did not change finishing time at all. It disrupted sleep after an evening session less β€” but that was measured with a questionnaire.

Andrey Leskovβ€’
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